2

Accessing the viscera: Technologies for interoception research

A gut sense for a microbial pattern regulates feeding

Magnetite Nanodiscs Activate Mechanotransductive Calcium Signaling in Diverse Cell Types

Shank3 mutation manifests in abnormal gastrointestinal morphology and function in mice

Multifunctional bioelectronics for brain–body circuits

Multifunctional Neural Probes Enable Bidirectional Electrical, Optical, and Chemical Recording and Stimulation In Vivo

Recording and modulation of neuronal activity enables the study of brain function in health and disease. While translational neuroscience relies on electrical recording and modulation techniques, mechanistic studies in rodent models leverage genetic …

Magnetoelectric nanodiscs enable wireless transgene-free neuromodulation

Deep brain stimulation with implanted electrodes has transformed neuroscience studies and treatment of neurological and psychiatric conditions. Discovering less invasive alternatives to deep brain stimulation could expand its clinical and research …

Fatigue-resistant hydrogel optical fibers enable peripheral nerve optogenetics during locomotion

We develop soft and stretchable fatigue-resistant hydrogel optical fibers that enable optogenetic modulation of peripheral nerves in naturally behaving animals during persistent locomotion. The formation of polymeric nanocrystalline domains within …

Multifunctional fibers enable modulation of cortical and deep brain activity during cognitive behavior in macaques

Recording and modulating neural activity in vivo enables investigations of the neurophysiology underlying behavior and disease. However, there is a dearth of translational tools for simultaneous recording and localized receptor-specific modulation. …

Multifunctional microelectronic fibers enable wireless modulation of gut and brain neural circuits

Progress in understanding brain–viscera interoceptive signaling is hindered by a dearth of implantable devices suitable for probing both brain and peripheral organ neurophysiology during behavior. Here we describe multifunctional neural interfaces …