Sharmelee (Sharm) completed both her undergraduate studies (2018) and PhD (2022) at the National University of Singapore. She has been working on mouse models of neurodegenerative diseases since undergraduate years which includes Parkinson’s disease, Alzheimer’s disease and Vascular dementia. For her PhD, Sharm pioneered the study on DNA methylation in a mouse model of Vascular dementia, an epigenetic mechanism that reflects the gene-environment interaction, in her lab. She demonstrated that intermittent fasting is able to slow down the disease progression of Vascular dementia in a mouse model through modulation of DNA methylation changes. In the Bioelectronics group, Sharm is excited to explore the gut-brain axis of Parkinson’s disease and investigate the mechanistic underpinnings of the disease. Apart from experiments, Sharm likes to advocate science to the public in layman terms through write-ups and public speaking/seminars. When not doing Science, Sharm likes to switch to the arts. She writes Tamil poems, knits, listens to music, hikes and loves to watch the clouds (nephophile).